Rat and sperm granuloma

Effects of water deprivation induced dehydration on the rat rete testis: Moderate to severe tubular atrophy is often accompanied by increased interstitial fluid sometimes termed edema Fig. Long-term effects of vasectomy on the pituitary-gonadal system of rat and mouse. Absence or incomplete development of the testis aplasia or hypoplasia is occasionally seen but is relatively uncommon. This is similar to the lesion in rodents. This is a particular problem in the dog and non-human primate.
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Sperm granuloma

Ultrastructure of the rat testis after vasectomy. Morphometric study of the testis and reproductive tract including sperm granuloma after vasectomy in mature rats. Asian Journal of Andrology ; More studies with the more commonly used rat model have shown, however, controversial results on whether and why the damage occurs. Acta europaea fertilitatis ; Most of these reasons relate to the significant morphological variability that is seen in the reproductive organs of all species as a result of normal physiological alterations: Quantitative pathologic changes in the human testis after vasectomy:
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Observation on multiple sperm granulomas in the rat

Effects of water deprivation induced dehydration on the rat rete testis: Lesions seen in young mature animals: References Patel A, Smith R. This publication is from a journal that may support self archiving. The rat testis after vasectomy.
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The mechanism of formation of most epididymal granulomas is unknown. Exposure of rats to high doses of testosterone given by implantation have also been shown to produce sperm granulomas after 35 days and it was argued that at high exposures testosterone compromises the integrity of the epididymis. Int J Fertil ; Other common background findings in the adult dog testis include swollen spermatocytes. Xanthoma and Xanthogranulomatous Prostatitis Xanthoma is a rare form of idiopathic granulomatous prostatitis that consists of a localized collection of cholesterol-laden histiocytes; it may also be seen in patients with hyperlipidemia. The ductal lumen is fully expanded with sperm and there are only occasional sloughed germ cells.
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